What is Methylsulfonylmethane (MSM)?

MSM is a compound found in humans, plants, and animals and can also be produced synthetically for medicinal use. A popular source of MSM is cow’s milk. Other food sources include coffee, swiss chard, corn, beer, tomatoes, and tea. Methylsulfonylmethane (MSM) is made by combining Dimethyl Sulfoxide (DMSO) and Hydrogen Peroxide and is a source of sulfur for methionine. Most commonly used for joint conditions, MSM helps to preserve and maintain connective tissues. It is primarily used to reduce inflammation in the body.

On a molecular level, MSM can reduce neutrophil production and therefore also reduce the production of oxidative free radicals.


MSM is a low-toxicity agent that can safely be used as an anti-inflammatory agent in a number of inflammatory conditions. A major benefit of MSM is that it can be used with most medications, supplements, or herbal agents.

Research has shown that MSM is beneficial for gastrointestinal concerns, pain, autoimmune disease, bladder inflammation, and fibromyalgia. It has been found that MSM can help to improve gastrointestinal motility and promote more frequent bowel movements in those individuals more susceptible to constipation. Studies have also shown improvement of Scleroderma with IV MSM treatments, especially when digestive organs are involved. Results have been documented with IV MSM and Rheumatoid Arthritis with improvement in joint stiffness, pain, and mobility.

MSM is also shown to have chemoprevention; the ability to prevent tumor growth by disrupting the tumor cell’s ability to proliferate through genetic activity.

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Benefits of MSM

MSM can help in the following conditions:

  • Lyme disease
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Certain autoimmune conditions
  • Asthma and Seasonal allergies

MSM is also used along with chemotherapeutic agents.

To find out if MSM can be beneficial in your condition, call our clinic today for a consultation.

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